[HTML][HTML] The effect of human antibacterial peptide LL-37 in the pathogenesis of chronic obstructive pulmonary disease

YY Jiang, W Xiao, MX Zhu, ZH Yang, XJ Pan… - Respiratory …, 2012 - Elsevier
BACKGROUND: Previous research has shown that innate immune system was more
important than the acquired immune system in the pathogenesis of COPD. LL-37 is the only
human cathelicidin identified so far. As an integral part of the innate immune system,
besides antibacterial activity, its chemotactic activity, damage repairing, influencing
apoptosis and its cytotoxicity are attracting people's attention. The aim of the present study
was to evaluate role of LL-37 in the pathogenesis of COPD. METHODS: ELISA and …
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